Pokemon Sun Sky and Moon Galaxy

It is about 15 years after the story of Pokémon Trainer Red. Red’s son lives in Pallet Town in the Kanto Region. But Red disappeared somewhere [However Red actually doesn’t play that much role in the game]. The protagonist of the game starts his journey when many things are totally changed in Kanto. After Professor Oak, Brock takes his place as the Pokémon Professor. The protagonist encounters some Pokémon which is not in the Kanto Pokedex. Eventually, he travels through Alola Region! But the main game takes its place in Kanto.

Source: TheGamesDB